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| Plant-specific insert ： ウィキペディア英語版 |
Plant-specific insert
The plant-specific insert (PSI) or plant-specific sequence (PSS) is an independent domain, exclusively found in plants, consisting of approximately 100 residues, found on the C-terminal lobe on some aspartic proteases (AP). The PSI, as an independent entity separate from its parent AP, is homologous to saposin and belongs to the saposin-like protein family (SAPLIP).
Although the PSI is grouped along proteins in the SAPLIP family, the PSI does not contain a proper saposin-like domain. This is due to a permutation of the N- and C-termini of the PSI, in which the termini are “swapped”. This has led to the PSI being termed a “swaposin” (a play-on-words of “swap” and “saposin”) although the tertiary structure still remains homologous to saposin and other members of the SAPLIP family.〔
==Structure==
Among plants, APs between different species are generally homologous exhibiting high sequence identity whilst maintaining a similar tertiary structure to pepsin.〔 As such, plant APs preserve the zymogenic form of the mature AP common to other aspartic proteases in which the zymogen is kept inactive until removal of the prosegment from the active cleft.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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